TY - JOUR JO - EuroIntervention TI - On-line three-dimensional OFDI guided PCI vs. angiography guided in bifurcation lesions: design and rationale of the randomized OPTIMUM trial AB - The aims of this trial is to determine the superiority of on-line three-dimensional optical frequency domain imaging (3D-OFDI) guided percutaneous coronary intervention (PCI) to angiography-guided PCI in bifurcation lesions. The OPTIMUM trial is a randomized, active control, superiority, and multi-center clinical trial. The primary endpoint is the post-procedural percentage of malapposed struts assessed by OFDI in the main branch bifurcation region after final kissing-balloon-dilatation. A total 106 patients will be randomly allocated to either 3D-OFDI or angiography guidance PCI. OPTIMUM trial will be the first prospective, randomised trial and evaluate the efficacy and safety of the on-line 3D-OFDI guided PCI. AU - Miyazaki Yosuke AU - Muramatsu Takashi AU - Asano Taku AU - Katagiri Yuki AU - Sotomi Yohei AU - Nakatani Shimpei AU - Takahashi Kuniaki AU - Kogame Norihiro AU - Higuchi Yoshiharu AU - Ishikawa Masato AU - Kyono Hiroyuki AU - Yano Masafumi AU - Ozaki Yukio AU - Serruys Patrick W. AU - Okamura Takayuki AU - Onuma Yoshinobu VL - IS - Y1 - 09/07/2019 Y1 - 2019 DOI - 10.4244/EIJ-D-18-00902 SP - KW - bifurcation KW - drug-eluting stent KW - other imaging modalities PB - Europa Digital & Publishing UR - https://eurointervention.pcronline.com/article/on-line-three-dimensional-ofdi-guided-pci-vs-angiography-guided-in-bifurcation-lesions-design-and-rationale-of-the-randomized-optimum-trial SN - 1774-024X ER -