TY - JOUR JO - EuroIntervention TI - Predictors of Non-Stenting Strategy for Acute Coronary Syndrome Caused by Plaque Erosion: 4-Year Outcomes of the EROSION Study AB - <p><strong>Aims: </strong>To test whether a non-stenting anti-thrombotic strategy was still effective at 4-year follow-up in patients enrolled in the EROSION study and to explore potential predictors of long-term prognosis.</p> <p><strong>Methods and results:</strong> Out of 55 patients who completed 1-month follow-up, 52 patients finished 4-year follow-up. The median duration was 4.8 years (4.2 - 5.8 years). The majority of patients remained free from events, and all patients were free from hard endpoints (death, myocardial infarction, stroke, bypass surgery, or heart failure). Only 1 patient had gastrointestinal bleeding, and 11 patients underwent elective target lesion revascularization (TLR). Patients in the non-TLR group had more optical coherence tomography (OCT) thrombus reduction from baseline to 1 month; 95% patients in the non-TLR group versus 45% in the TLR group (p=0.001) met the primary endpoint (thrombus volume reduction &gt;50%). Consistent with the OCT findings, angiographic results showed that the TLR group had less improvement in diameter stenosis (p=0.014) at 1 month compared with non-TLR group.</p> <p><strong>Conclusions:</strong> Four-year follow-up findings reconfirmed the safety of an anti-thrombotic therapy without stenting for erosion-caused acute coronary syndrome. Patients with better response to anti-thrombotic therapy in the first month were less likely to require stent implantation during the next four years.</p> <p>&nbsp;</p> AU - He Luping AU - Qin Yuhan AU - Xu Yishuo AU - Hu Sining AU - Wang Yini AU - Zeng Ming AU - Feng Xue AU - Liu Qi AU - Syed Ikramullah AU - Demuyakor Abigail AU - Zhao Chen AU - Chen Xi AU - Li Zhaoyue AU - Meng Wei AU - Xu Maoen AU - Liu Huimin AU - Ma Lijia AU - Dai Jiannan AU - Xing Lei AU - Yu Huai AU - Hou Jingbo AU - Jia Haibo AU - Mintz Gary S. AU - Yu Bo VL - IS - Y1 - 10/11/2020 Y1 - 2020 DOI - 10.4244/EIJ-D-20-00299 SP - KW - acs / nste-acs KW - stemi KW - optical coherence tomography PB - Europa Digital & Publishing UR - https://eurointervention.pcronline.com/article/predictors-of-non-stenting-strategy-for-acute-coronary-syndrome-caused-by-plaque-erosion-4-year-outcomes-of-the-erosion-study SN - 1774-024X ER -