TY - JOUR JO - EuroIntervention TI - Thirty-day outcomes of the Cardioband tricuspid system for patients with symptomatic functional tricuspid regurgitation: The TriBAND study AB - <p><strong>Background:</strong> Severe tricuspid regurgitation (TR) has limited treatment options and is associated with high morbidity and mortality.</p> <p><strong>Aims:</strong> We evaluated the safety and effectiveness of the Cardioband tricuspid valve reconstruction system from the ongoing European single-arm, multicentre, prospective TriBAND post-market clinical follow-up study.</p> <p><strong>Methods:</strong> Eligible patients had chronic symptomatic functional TR despite diuretic therapy and were deemed candidates for transcatheter tricuspid repair by the local Heart Team.</p> <p><strong>Results:</strong> Sixty-one patients had &ge;severe functional TR. At baseline, 85% of patients were in NYHA Class III-IV, 94% had &ge;severe TR (core laboratory-assessed) with 6.8% EuroSCORE II and 53% LVEF. Device success was 96.7%. At discharge, 59% (p&lt;0.001) of patients achieved &le;moderate TR and 78% had at least one grade TR reduction. At 30 days, all-cause mortality and composite MAE rates were 1.6% and 19.7%, respectively; septolateral annular diameter was reduced by 20%, where 69% of patients achieved &le;moderate TR and 85% of patients had at least one grade TR reduction (all p&lt;0.001). Mid-RVEDD, RA volume, and IVC diameter decreased by 10% (p=0.005), 21% (p&lt;0.001), and 11% (p=0.022), respectively; 74% were in NYHA Class I-II (p&lt;0.001) with improvements in overall KCCQ score by 17 points (p&lt;0.001).</p> <p><strong>Conclusions:</strong> In the TriBAND study, the Cardioband tricuspid system demonstrated favourable outcomes at discharge and 30 days in a challenging patient population with symptomatic &ge;severe functional TR. Results showed significant reductions in annular diameter and TR severity, accompanied by early evidence of right heart remodelling and improvements in functional status and quality of life.</p> AU - Nickenig Georg AU - Friedrichs P. Kai AU - Baldus Stephan AU - Arnold Martin AU - Seidler Tim AU - Hakmi Samer AU - Linke Axel AU - Schäfer Ulrich AU - Dreger Henryk AU - Reinthaler Markus AU - von Bardeleben Ralph Stephan AU - Möllmann Helge AU - Weber Marcel AU - Roder Fabian AU - Körber Maria Isabel AU - Landendinger Melanie AU - Wolf Frieder AU - Alessandrini Hannes AU - Sveric Krunoslav AU - Schewel Dimitry AU - Romero-Dorta Elena AU - Kasner Mario AU - Dahou Abdellaziz AU - Hahn T. Rebecca AU - Windecker Stephan VL - 17 IS - 10 Y1 - 19/11/2021 Y1 - 2021 DOI - 10.4244/EIJ-D-21-00300 SP - 809 EP - 817 KW - tricuspid disease KW - femoral KW - transthoracic echocardiogram KW - transoesophageal echocardiogram PB - Europa Digital & Publishing SE - Interventions for valvular disease and heart failure - Mini focus on tricuspid regurgitation UR - https://eurointervention.pcronline.com/article/thirty-day-outcomes-of-the-cardioband-tricuspid-system-for-patients-with-symptomatic-functional-tricuspid-regurgitation-the-triband-study SN - 1774-024X ER -