TY - JOUR JO - EuroIntervention TI - Long-term outcomes of peripheral atherectomy for femoropopliteal endovascular interventions AB - <p><strong>Background:</strong> The use of atherectomy during peripheral endovascular interventions (PVI) has increased dramatically, but data regarding its safety and effectiveness are lacking.&nbsp;</p> <p><strong>Aims:</strong> This study sought to determine the long-term safety of atherectomy in contemporary practice.&nbsp;</p> <p><strong>Methods:</strong> Medicare fee-for-service beneficiaries who underwent femoropopliteal artery PVI from 2015-2018 were identified in a 100% sample of inpatient, outpatient, and carrier file data using procedural claims codes. The primary exposure was the use of atherectomy. Inverse probability of treatment weighting was used to adjust for measured differences in patient populations. Kaplan-Meier methods and multivariable Cox proportional hazards regression were used to compare outcomes.&nbsp;</p> <p><strong>Results:</strong> Among 168,553 patients who underwent PVI, 59,142 (35.1%) underwent atherectomy. The mean patient age was 77.0&plusmn;7.6 years, 44.9% were female, 81.9% were white, and 46.7% had chronic limb-threatening ischaemia. Over a median follow-up time of 993 days (interquartile range 319-1,377 days), atherectomy use was associated with no difference in the risk of either the composite endpoint of death and amputation (adjusted hazard ratio [aHR] 0.99, 95% confidence interval [CI]: 0.97-1.01; p=0.19) or of major adverse limb events (aHR 1.02, 95% CI: 0.99-1.05; p=0.26). Patients who underwent atherectomy had a modest reduction in the risk of subsequently undergoing amputation or surgical revascularisation (aHR 0.92, 95% CI: 0.90-0.94; p&lt;0.01) but an increase in the risk of undergoing a subsequent PVI (aHR 1.19, 95% CI: 1.16-1.21; p&lt;0.01).</p> <p><strong>Conclusions:</strong> The use of atherectomy during femoropopliteal artery PVI was not associated with an increase in the risk of long-term adverse safety outcomes among patients with peripheral artery disease.</p> AU - Krawisz K. Anna AU - Raja Aishwarya AU - Jones W. Schuyler AU - Schneider Peter AU - Shen Changyu AU - Schermerhorn Marc AU - Secemsky A. Eric VL - IS - Y1 - 14/11/2022 Y1 - 2022 DOI - 10.4244/EIJ-D-22-00609 SP - KW - atherectomy KW - claudication KW - critical limb ischaemia KW - femoropopliteal disease PB - Europa Digital & Publishing UR - https://eurointervention.pcronline.com/article/long-term-outcomes-of-peripheral-atherectomy-for-femoropopliteal-endovascular-interventions SN - 1774-024X ER -